Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764794 | 0.90 | MAPT (0.48) | MAPTKDM4ECYP3A4LMNAHIF1A | |
| SCHEMBL1770055 | 0.79 | KDM4E (0.41) | MAPTKDM4ESMN1; SMN2ERN1ADRB2 | |
| SCHEMBL17375503 | 0.77 | MAPT (0.46) | MAPTKDM4ECYP3A4LMNAHIF1A | |
| SCHEMBL13154670 | 0.76 | CHRNB2 (0.33) | KDM4ECYP3A4CYP1A2 | |
| SCHEMBL13154669 | 0.75 | PKM (0.34) | — | |
| SCHEMBL13154673 | 0.74 | ADRA2A (0.36) | MAPTKDM4ECYP3A4LMNABLM | |
| SCHEMBL27896391 | 0.74 | MAPT (0.50) | MAPTKDM4ECYP3A4LMNAHIF1A | |
| SCHEMBL634543 | 0.72 | HSD17B10 (0.42) | CYP3A4HIF1ATSHRNFKB1NCF1 | |
| SCHEMBL31668742 | 0.72 | HSD17B10 (0.42) | CYP3A4HIF1ATSHRNFKB1NCF1 | |
| SCHEMBL13154645 | 0.71 | LMNA (0.52) | MAPTKDM4ECYP3A4LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820316-B | Chiral indolo-dihydropyridoindole compound and synthesis method thereof | 江苏师范大学 | 2024-06-28 | — | — | CN | claimed |
| CN-117820316-A | Chiral indolo-dihydropyridoindole compound and synthesis method thereof | 江苏师范大学 | 2024-04-05 | — | — | CN | claimed |
| JP-51118800-A | — | — | None | — | — | JP | disclosed |
| JP-51118798-A | — | — | None | — | — | JP | disclosed |
| JP-51118797-A | — | — | None | — | — | JP | disclosed |
| JP-51118799-A | — | — | None | — | — | JP | disclosed |
| CN-117820316-B | Chiral indolo-dihydropyridoindole compound and synthesis method thereof | 江苏师范大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-117820316-B | Chiral indolo-dihydropyridoindole compound and synthesis method thereof | 江苏师范大学 | 2024-06-28 | — | — | CN | disclosed |
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | UDC IRELAND LIMITED (IE) | 2024-05-07 | — | — | US | disclosed |
| CN-117820316-A | Chiral indolo-dihydropyridoindole compound and synthesis method thereof | 江苏师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-117820316-A | Chiral indolo-dihydropyridoindole compound and synthesis method thereof | 江苏师范大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2002036113-A1 | COMPOSITION COMPRISING: SEROTONIN RECEPTOR ANTAGONISTS (5HT-2, 5HT-3) AND AGONIST (5HT-4) | RESPIRATORIUS AB (SE) | 2002-05-10 | — | — | WO | disclosed |
| US-5268472-A | Monopersulfate salt | AUSIMONT S.P.A. (IT) | 1993-12-07 | — | — | US | disclosed |
| EP-0340755-B1 | MONOPERSULFATES OF NITROGEN CONTAINING HETEROCYCLIC (POLY)PERCARBOXYLIC ACIDS | AUSIMONT S.p.A. (IT) | 1993-09-01 | — | — | EP | disclosed |
| EP-0340755-A1 | Monopersulfates of nitrogen containing heterocyclic (poly)percarboxylic acids | AUSIMONT S.p.A. (IT) | 1989-11-08 | — | — | EP | disclosed |
| US-4091102-A | Anti-depressant trans-hexahydropyrido[3,4-b]indoles | ENDO LABORATORIES, INC. (US) | 1978-05-23 | — | — | US | disclosed |
| JP-S51118797-A | METHOD FOR PREPARING PYRIDOINDOLE AND AZEPINOINDOLE DERIVATIVES | SANKYO CO LTD | 1976-10-18 | — | — | JP | disclosed |
| JP-S51118800-A | METHOD FOR PREPARING PYRIDOINDOLE DERIVATIVES | SANKYO CO LTD | 1976-10-18 | — | — | JP | disclosed |
| JP-S51118798-A | METHOD FOR PREPARING PYRIDOINDOLE DERIVATIVES | SANKYO CO LTD | 1976-10-18 | — | — | JP | disclosed |
| JP-S51118799-A | METHOD FOR PREPARING PYRIDINDOLE DERIVATIVES | SANKYO CO LTD | 1976-10-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | OCIAD2, OCIAD1, ICOSLG | MAPT 414/4885KDM4E 4325/4885CYP3A4 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.