Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778932 | 0.74 | GSK3A (0.69) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL435053 | 0.68 | CYP4F2 (0.68) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL304455 | 0.66 | CYP4F2 (0.74) | KDM4EHPGDHSD17B10ALDH1A1GLA | |
| Ethane SCHEMBL27846059 | 0.65 | CYP4F2 (0.72) | KDM4EHPGDHSD17B10ALDH1A1GLA | |
| SCHEMBL28309812 | 0.65 | CCNC (0.53) | ALDH1A1GAAKMT2ACA12CA1 | |
| SCHEMBL2080801 | 0.63 | CYP4F2 (0.47) | KDM4EHPGDHSD17B10ALDH1A1GLA | |
| SCHEMBL8113995 | 0.63 | FAAH (0.53) | TNFALDH1A1MAPT | |
| SCHEMBL7253117 | 0.63 | GSK3A (0.69) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL13216734 | 0.62 | L3MBTL1 (0.50) | KDM4EHPGDHSD17B10ALDH1A1GLA | |
| SCHEMBL10837603 | 0.62 | CYP4F2 (0.43) | TNFALDH1A1L3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233486-A1 | Azaindoles | Aventis Pharma Limited (GB) | 2010-09-29 | — | — | EP | disclosed |