Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10216755 | 0.89 | PTPRB (0.45) | FAAHKCNQ2KCNQ3CYP1A2CYP3A4 | |
| SCHEMBL3446920 | 0.82 | KCNQ3 (0.44) | KCNQ2KCNQ3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10216752 | 0.81 | PTPRB (0.45) | FAAHKCNQ2KCNQ3CYP1A2CYP3A4 | |
| SCHEMBL13158480 | 0.81 | AVPR2 (0.38) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL10217156 | 0.78 | CA12 (0.47) | FAAHKCNQ2KCNQ3CYP1A2CYP3A4 | |
| SCHEMBL3447257 | 0.77 | PTPRB (0.45) | FAAHKCNQ2KCNQ3CYP1A2CYP3A4 | |
| SCHEMBL28429965 | 0.76 | FAAH (0.48) | FAAHCYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL20792320 | 0.76 | FAAH (0.45) | FAAHCYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10217130 | 0.76 | PTPRB (0.47) | FAAHKCNQ2KCNQ3CYP1A2CYP3A4 | |
| SCHEMBL3447661 | 0.74 | CYP1A2 (0.45) | FAAHKCNQ2KCNQ3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010105770-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |