Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13159611 | 0.92 | AVPR2 (0.38) | AVPR2AVPR1ACNR2CTSKMMP7 | |
| SCHEMBL10216773 | 0.88 | AVPR2 (0.46) | AVPR2AVPR1ACNR2MMP7TSHR | |
| SCHEMBL10216767 | 0.81 | AVPR2 (0.45) | AVPR2AVPR1ACNR2MMP7TSHR | |
| SCHEMBL13158316 | 0.81 | FAAH (0.44) | CTSKTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3448694 | 0.80 | CNR2 (0.46) | AVPR2AVPR1ACNR2MMP7TSHR | |
| SCHEMBL10217129 | 0.75 | LMNA (0.47) | AVPR2AVPR1ACNR2TSHRHPGD | |
| SCHEMBL10270827 | 0.74 | LMNA (0.44) | CTSKTSHRHPGDSMN1; SMN2LMNA | |
| SCHEMBL10217111 | 0.73 | CA12 (0.41) | AVPR2AVPR1ACTSKTSHRHPGD | |
| SCHEMBL3446813 | 0.72 | CNR2 (0.45) | CNR2MMP7TSHRCYP1A2CYP3A4 | |
| SCHEMBL10216855 | 0.72 | LMNA (0.48) | AVPR2AVPR1ACNR2CTSKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010105770-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |