SCHEMBL1316052

SCHEMBL1316052

O=C(O)c1cc2c(cc1OCc1ccccc1)OCO2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.58
FOLH1 Q04609 2/20 0.55
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
NPC1 O15118 1/20 0.49
TP53 P04637 1/20 0.49
MAPT P10636 1/20 0.49
TSHR P16473 1/20 0.49
RAB9A P51151 1/20 0.49
ATM Q13315 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MAOA P21397 3/20 0.48
MCL1 Q07820 3/20 0.47
PTGER1 P34995 2/20 0.46
EDNRB P24530 2/20 0.46
EDNRA P25101 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1316544 0.91 MAOB (0.58) MAOBFOLH1ALDH1A1L3MBTL1KDM4E
SCHEMBL10565899 0.89 MAOB (0.56) MAOBALDH1A1L3MBTL1KDM4ENPC1
SCHEMBL9789582 0.83 KMT2A (0.51) MAOBALDH1A1L3MBTL1KDM4EPOLB
SCHEMBL21363636 0.83 MAOB (0.59) MAOBALDH1A1L3MBTL1KDM4ENPC1
SCHEMBL10089235 0.83 FOLH1 (0.69) MAOBFOLH1ALDH1A1L3MBTL1KDM4E
SCHEMBL7910955 0.82 MAOB (0.66) MAOBL3MBTL1NPC1RAB9AKMT2A
SCHEMBL29828748 0.81 SCN4A (0.47) MAOBALDH1A1KDM4EPOLBNPC1
SCHEMBL27148327 0.81 SCN4A (0.47) MAOBALDH1A1KDM4EPOLBNPC1
SCHEMBL27032843 0.81 SCN4A (0.47) MAOBALDH1A1KDM4EPOLBNPC1
SCHEMBL9789581 0.81 MAOB (0.59) MAOBALDH1A1L3MBTL1NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 MAOB 2284/4885FOLH1 3884/4885ALDH1A1 813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.