SCHEMBL1316219

SCHEMBL1316219

CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(I)ccc1OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LRRK2 Q5S007 15/20 0.46
▸ HDAC1 Q13547 1/20 0.42
▸ SGMS2 Q8NHU3 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ SMPD1 P17405 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1317041 0.93 HDAC1 (0.43) LRRK2HDAC1SGMS2MEN1KMT2A
SCHEMBL1317653 0.91 LRRK2 (0.47) LRRK2HDAC1SGMS2MEN1KMT2A
SCHEMBL1317477 0.90 LRRK2 (0.46) LRRK2HDAC1SGMS2MEN1KMT2A
SCHEMBL1316377 0.90 LRRK2 (0.55) LRRK2TDP1L3MBTL1
SCHEMBL1316898 0.89 MCL1 (0.47) LRRK2HDAC1SGMS2MEN1KMT2A
SCHEMBL1316125 0.89 LRRK2 (0.61) LRRK2
SCHEMBL1317519 0.88 LRRK2 (0.51) LRRK2HDAC1SGMS2
SCHEMBL1316883 0.88 LRRK2 (0.44) LRRK2HDAC1SGMS2MEN1KMT2A
SCHEMBL28790756 0.88 LRRK2 (0.44) LRRK2HDAC1L3MBTL1
SCHEMBL1319452 0.88 LRRK2 (0.44) LRRK2HDAC1SGMS2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 — — US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 — — US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 LRRK2 1813/4885HDAC1 73/4885SGMS2 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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