SCHEMBL1317041

SCHEMBL1317041

CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(I)cc1OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 1/20 0.43
▸ SGMS2 Q8NHU3 2/20 0.42
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ MCL1 Q07820 1/20 0.41
▸ RXRA P19793 2/20 0.41
▸ NR1H2 P55055 2/20 0.41
▸ NR1H3 Q13133 2/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ LRRK2 Q5S007 1/20 0.41
▸ GAA P10253 1/20 0.40
▸ KIFC1 Q9BW19 1/20 0.40
▸ ACLY P53396 3/20 0.39
▸ SMPD1 P17405 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1316898 0.94 MCL1 (0.47) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1316219 0.93 LRRK2 (0.46) HDAC1SGMS2MEN1KMT2ATDP1
SCHEMBL1317655 0.91 GAA (0.46) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1315346 0.90 HDAC1 (0.42) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1316825 0.89 LRRK2 (0.52) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1316899 0.89 GAA (0.43) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1316105 0.88 LRRK2 (0.45) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1317043 0.88 NR1H2 (0.43) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1317653 0.86 LRRK2 (0.47) HDAC1SGMS2MEN1KMT2AMCL1
SCHEMBL1318330 0.86 LRRK2 (0.52) HDAC1SGMS2LRRK2SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 — — US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 — — US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 HDAC1 73/4885SGMS2 4244/4885MEN1 3020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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