Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 19/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316798 | 0.90 | LRRK2 (0.57) | LRRK2CYP3A4SLCO1B1KCNH2 | |
| SCHEMBL1316332 | 0.89 | LRRK2 (0.56) | LRRK2CYP3A4SLCO1B1KCNH2 | |
| SCHEMBL1315545 | 0.88 | LRRK2 (0.58) | LRRK2CYP3A4SLCO1B1KCNH2 | |
| SCHEMBL1317027 | 0.87 | LRRK2 (0.47) | LRRK2CYP3A4SLCO1B1KCNH2 | |
| SCHEMBL1316686 | 0.87 | BACE1 (0.43) | CYP3A4BACE1 | |
| SCHEMBL12117860 | 0.87 | BACE1 (0.43) | CYP3A4BACE1 | |
| SCHEMBL1316012 | 0.86 | LRRK2 (0.58) | LRRK2CYP3A4SLCO1B1KCNH2 | |
| SCHEMBL1315355 | 0.84 | LRRK2 (0.48) | LRRK2CYP3A4SLCO1B1KCNH2 | |
| SCHEMBL1319536 | 0.84 | LRRK2 (0.48) | LRRK2CYP3A4SLCO1B1KCNH2 | |
| SCHEMBL1317921 | 0.83 | LRRK2 (0.49) | LRRK2CYP3A4SLCO1B1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333757-B | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2014-11-26 | — | — | CN | disclosed |
| US-8492582-B2 | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | COL14A1, COL2A1, COL1A1 | LRRK2 1813/4885CYP3A4 3293/4885SLCO1B1 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.