Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBK | Q96KB5 | 14/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162648 | 0.85 | NPC1 (0.59) | — | |
| SCHEMBL13162900 | 0.84 | CHRM1 (0.65) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL6175361 | 0.84 | NPC1 (0.61) | — | |
| Hydrochloric Acid SCHEMBL2882908 | 0.83 | OPRM1 (0.53) | PBKCHEK1 | |
| SCHEMBL8297083 | 0.82 | HPGD (0.57) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL2423748 | 0.81 | KMT2A (0.60) | PBKCHEK1CHRM2CHRM3 | |
| SCHEMBL8719970 | 0.81 | KMT2A (0.60) | PBKCHEK1CHRM2CHRM3 | |
| SCHEMBL8719751 | 0.81 | KMT2A (0.60) | PBKCHEK1CHRM2CHRM3 | |
| SCHEMBL17888464 | 0.79 | MMP13 (0.61) | PBK | |
| SCHEMBL1278937 | 0.77 | NPC1 (0.69) | PBKCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | TRPV1, FGFR3, GPR17 | PBK 3810/4885CHEK1 3336/4885SLC6A2 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.