Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.67 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967304 | 0.85 | NPY2R (0.74) | NPY2RKDM4ERECQLMAPTKMT2A | |
| SCHEMBL13856567 | 0.81 | MAPT (1.00) | KDM4EMAPTKMT2ANPSR1USP2 | |
| SCHEMBL13949529 | 0.76 | MEN1 (0.66) | NPY2RMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL1594391 | 0.75 | KMT2A (0.66) | NPY2RKDM4EMAPTKMT2ANPSR1 | |
| SCHEMBL7651873 | 0.75 | KMT2A (0.69) | KDM4ERECQLMAPTKMT2ANPSR1 | |
| SCHEMBL1593432 | 0.74 | KMT2A (0.64) | NPY2RKDM4EMAPTKMT2ANPSR1 | |
| SCHEMBL6566906 | 0.74 | POLB (0.66) | NPY2RKDM4EMAPTKMT2ANPSR1 | |
| SCHEMBL7655884 | 0.74 | KMT2A (0.71) | KDM4ERECQLMAPTKMT2ANPSR1 | |
| SCHEMBL7649651 | 0.72 | ALDH1A1 (0.65) | KDM4ERECQLMAPTKMT2ANPSR1 | |
| SCHEMBL6454551 | 0.72 | KDM4E (0.66) | NPY2RKDM4ERECQLMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | UGCG, MAGT1, STT3B | NPY2R 2970/4885KDM4E 2180/4885RECQL 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.