SCHEMBL812440

SCHEMBL812440

Cc1ccc(C)c2nc3ccccc3nc12

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 6/20 0.56
MAPT P10636 4/20 0.53
RAB9A P51151 2/20 0.46
KMT2A Q03164 2/20 0.46
NPC1 O15118 2/20 0.46
MEN1 O00255 1/20 0.46
HCRTR1 O43613 1/20 0.46
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7074871 0.83 NQO2 (0.42) NQO2MAPTRAB9AKMT2ANPC1
SCHEMBL5798945 0.83 NQO2 (0.81) NQO2MAPTRAB9AKMT2ANPC1
SCHEMBL28705258 0.83 NQO2 (0.42) NQO2MAPTRAB9AKMT2ANPC1
SCHEMBL183009 0.82 NQO2 (0.57) NQO2MAPTRAB9AKMT2ANPC1
Bromide SCHEMBL11421481 0.80 NQO2 (0.55) NQO2MAPTRAB9AKMT2ANPC1
SCHEMBL7567602 0.80 ALDH1A1 (0.61) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL13181658 0.80 NQO2 (0.46) NQO2MAPTRAB9ANPC1ALDH1A1
SCHEMBL1010318 0.79 MAPT (0.55) NQO2MAPTRAB9AKMT2ANPC1
Phenazine SCHEMBL29098643 0.79 MAPT (0.55) NQO2MAPTRAB9AKMT2ANPC1
SCHEMBL29645243 0.79 MAPT (0.55) NQO2MAPTRAB9AKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802975-B2 Compounds for organic thin-film solar cells and organic thin-film solar cells Wong, Ken-Tsung (TW) 2014-08-12 US disclosed
US-8802975-B2 Compounds for organic thin-film solar cells and organic thin-film solar cells Wong, Ken-Tsung (TW) 2014-08-12 US disclosed
US-20130027636-A1 CLASS OF BRIDGED BIPHENYLENE POLYMERS SUMITOMO CHEMICAL CO., LTD. (JP) 2013-01-31 US disclosed
US-20130027636-A1 CLASS OF BRIDGED BIPHENYLENE POLYMERS SUMITOMO CHEMICAL CO., LTD. (JP) 2013-01-31 US disclosed
WO-2013016187-A1 COMPOUNDS FOR ORGANIC THIN-FILM SOLAR CELLS AND ORGANIC THIN-FILM SOLAR CELLS WONG KEN-TSUNG 2013-01-31 WO disclosed
US-20130019949-A1 COMPOUNDS FOR ORGANIC THIN-FILM SOLAR CELLS AND ORGANIC THIN-FILM SOLAR CELLS Lin, Hao-Wu 2013-01-24 US disclosed
US-20130019949-A1 COMPOUNDS FOR ORGANIC THIN-FILM SOLAR CELLS AND ORGANIC THIN-FILM SOLAR CELLS Lin, Hao-Wu 2013-01-24 US disclosed
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-18 US disclosed
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-18 US disclosed
US-8247800-B2 Triarylamine containing polymers and electronic devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-21 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 US disclosed
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 US disclosed
US-20080011353-A1 Triarylamine Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-17 US disclosed
US-20080011353-A1 Triarylamine Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-17 US disclosed
EP-1576032-B1 TRICYCLIC ARYLAMINE MONOMER AND POLYMERS AND DEVICES THEREOF DOW GLOBAL TECHNOLOGIES INC (US) 2007-10-17 EP disclosed
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon DOW GLOBAL TECHNOLOGIES INC. 2007-05-10 US disclosed
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon DOW GLOBAL TECHNOLOGIES INC. 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES NAT1, SAT1, RIF1 NQO2 2310/4885MAPT 1378/4885RAB9A 2990/4885
US-20120264977-A1 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES NAT1, AHR, AR NQO2 4105/4885MAPT 3376/4885RAB9A 2589/4885
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon THEM6, PCNA, PARG NQO2 2203/4885MAPT 107/4885RAB9A 1267/4885
US-20090001324-A1 Salicylate Substituted Conjugated Polymers and Devices TLR9, TLR5, TLR1 NQO2 4316/4885MAPT 342/4885RAB9A 4271/4885
US-20130019949-A1 COMPOUNDS FOR ORGANIC THIN-FILM SOLAR CELLS AND ORGANIC THIN-FILM SOLAR CELLS CDH1, FTO, SUN2 NQO2 2316/4885MAPT 1180/4885RAB9A 542/4885
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices PYM1, KCNMB4, BRD9 NQO2 3715/4885MAPT 2713/4885RAB9A 1613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.