Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596153 | 0.83 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL676520 | 0.82 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL22783492 | 0.81 | TSHR (0.62) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL17466589 | 0.80 | ALDH1A1 (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21242412 | 0.80 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2759322 | 0.80 | ALDH1A1 (0.53) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL20083275 | 0.79 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1532920 | 0.79 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1286178 | 0.78 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11792800 | 0.78 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303649-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION FOR OPTICAL MATERIAL, CURED PRODUCT, AND PRODUCTION METHOD | KANEKA CORPORATION (JP) | 2013-11-14 | — | — | US | disclosed |
| US-8389630-B2 | Curable composition | KANEKA CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20100222446-A1 | CURABLE COMPOSITION FOR BOTH PHOTORADICAL CURING AND THERMAL RADICAL CURING | KANEKA CORPORATION (JP) | 2010-09-02 | — | — | US | disclosed |