SCHEMBL676520

SCHEMBL676520

C=CC(=O)OCCC(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
ALDH1A1 P00352 4/20 0.56
TP53 P04637 3/20 0.56
HIF1A Q16665 3/20 0.56
CYP3A4 P08684 2/20 0.56
HSD17B10 Q99714 1/20 0.56
HPGD P15428 1/20 0.50
THRB P10828 2/20 0.46
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SLC13A3 Q8WWT9 1/20 0.34
HTT P42858 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10175676 0.89 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10175679 0.89 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL18596153 0.88 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8373745 0.88 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11792800 0.88 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9301638 0.86 TSHR (0.67) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL24465248 0.84 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10339369 0.84 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30294088 0.84 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9302438 0.84 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549175-B Multifunctional conductive ionic liquid gel and preparation method and application thereof 华南理工大学 2022-04-22 CN claimed
CN-113549175-A Multifunctional conductive ionic liquid gel and preparation method and application thereof 华南理工大学 2021-10-26 CN claimed
US-20070013869-A1 HYBRID CONTACT LENS SYSTEM AND METHOD DAHI ALI 2007-01-18 US claimed
EP-0242080-A2 Copolymer compositions PARAGON OPTICAL INC (US) 1987-10-21 EP claimed
US-4387203-A COPOLYMER OF AN UNSATURATED NITRILE, CONJUGATED DIENE AND UNSATURATED FLUORINE COMPOUND GASOLINE RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-06-07 US claimed
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER OREAL (FR) 2025-12-18 US disclosed
WO-2025033541-A1 RESIN COMPOSITION, PELLETS, AND MOLDED ARTICLE 三菱ケミカル株式会社 2025-02-13 WO disclosed
US-12220479-B2 Suncare formulation ROHM AND HAAS COMPANY (US) 2025-02-11 US disclosed
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER L'OREAL (FR) 2025-02-06 US disclosed
US-12151015-B2 Color cosmetic formulation DOW GLOBAL TECHNOLOGIES LLC (US) 2024-11-26 US disclosed
EP-4452193-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER L'OREAL (FR) 2024-10-30 EP disclosed
US-12128125-B2 Polymer blend DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-29 US disclosed
US-5908721-A COLOR FILTER SHARP KABUSHIKI KAISHA (JP) 1999-06-01 US disclosed
EP-0583918-B1 Reflection preventing film and process for forming resist pattern using the same JAPAN SYNTHETIC RUBBER CO LTD (JP) 1999-03-10 EP disclosed
US-5410005-A Comprising acrylic amide and ester copolymers and their salts, having carboxyl and sulfonic acid groups as well as fluoro JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-04-25 US disclosed
US-5336582-A Electrophotographic image formation comprising an arylamine in a charge transport layer and an encapsulated toner FUJI XEROX CO., LTD. (JP) 1994-08-09 US disclosed
US-5300388-A Toner for electrophotography and process for producing the same FUJI XEROX CO., LTD. (JP) 1994-04-05 US disclosed
EP-0583918-A2 Reflection preventing film and process for forming resist pattern using the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-02-23 EP disclosed
EP-0242080-A2 Copolymer compositions PARAGON OPTICAL INC (US) 1987-10-21 EP disclosed
US-4387203-A COPOLYMER OF AN UNSATURATED NITRILE, CONJUGATED DIENE AND UNSATURATED FLUORINE COMPOUND GASOLINE RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12128125-B2 Polymer blend MMAB, MMS19, C9 TSHR 2929/4885ALDH1A1 2174/4885TP53 2343/4885
US-12151015-B2 Color cosmetic formulation FDFT1, CAD, SCD5 TSHR 2892/4885ALDH1A1 395/4885TP53 1117/4885
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER H1-0, PARN, FASN TSHR 1030/4885ALDH1A1 2361/4885TP53 150/4885
US-12220479-B2 Suncare formulation MMS19, TLR7, CD40LG TSHR 3879/4885ALDH1A1 771/4885TP53 1495/4885
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER CCNO, CUTA, SQLE TSHR 3701/4885ALDH1A1 1418/4885TP53 715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.