SCHEMBL1316907

SCHEMBL1316907

CC(=O)Oc1ccc(N2CCCCC2)cc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.60
PTGS2 P35354 2/20 0.60
CFD P00746 2/20 0.56
IP6K1 Q92551 1/20 0.56
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.47
HPGD P15428 2/20 0.47
TSHR P16473 2/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
GGT1 P19440 1/20 0.47
BLM P54132 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
MRGPRX4 Q96LA9 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12121567 0.84 MEN1 (0.54) PTGS1PTGS2CFDIP6K1KDM4E
SCHEMBL13205909 0.81 KMT2A (0.44) PTGS1PTGS2CFDIP6K1KDM4E
SCHEMBL12121307 0.79 S1PR3 (0.52) IP6K1KDM4EALDH1A1HPGDKEAP1
SCHEMBL1318540 0.76 LRRK2 (0.64) IP6K1KDM4EALDH1A1MRGPRX4MEN1
SCHEMBL1317583 0.75 IP6K1 (0.66) PTGS2IP6K1KDM4EALDH1A1HSD17B10
SCHEMBL2304941 0.74 IP6K1 (0.59) IP6K1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL8871236 0.74 IP6K1 (0.97) IP6K1KDM4EALDH1A1HSD17B10HPGD
SCHEMBL16715329 0.73 CFD (1.00) PTGS1PTGS2CFDKDM4EALDH1A1
SCHEMBL25027 0.73 CFD (0.73) PTGS1PTGS2CFDKDM4EALDH1A1
SCHEMBL27571515 0.73 IP6K1 (0.62) IP6K1KDM4EALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed
WO-2010087430-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF 富山化学工業株式会社 (JP) 2010-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 PTGS1 1453/4885PTGS2 2612/4885CFD 2776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.