SCHEMBL1317033

SCHEMBL1317033

CN(C)CCN(C)c1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)OC(C)(C)C)c(OCc2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIFC1 Q9BW19 2/20 0.41
▸ HDAC1 Q13547 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ HDAC2 Q92769 1/20 0.38
▸ CYP19A1 P11511 1/20 0.38
▸ RXRA P19793 1/20 0.37
▸ NR1H2 P55055 1/20 0.37
▸ NR1H3 Q13133 1/20 0.37
▸ SGMS2 Q8NHU3 1/20 0.37
▸ KIT P10721 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ MCL1 Q07820 1/20 0.37
▸ LRRK2 Q5S007 2/20 0.37
▸ MCHR1 Q99705 2/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1316105 0.91 LRRK2 (0.45) KIFC1HDAC1KDM4EALDH1A1CYP1A2
SCHEMBL1316898 0.88 MCL1 (0.47) KIFC1HDAC1KDM4EALDH1A1CYP1A2
SCHEMBL12117827 0.86 MCHR1 (0.42) HDAC1ALDH1A1CYP1A2HDAC2MEN1
SCHEMBL1316203 0.86 HDAC1 (0.44) HDAC1KDM4EHDAC2MCHR1
SCHEMBL12117836 0.85 HDAC1 (0.41) HDAC1ALDH1A1CYP1A2HDAC2MEN1
SCHEMBL12117848 0.85 HDAC1 (0.45) HDAC1KDM4EHDAC2MCHR1
SCHEMBL1317655 0.85 GAA (0.46) KIFC1HDAC1RXRANR1H2NR1H3
SCHEMBL1316474 0.84 LRRK2 (0.51) HDAC1CYP19A1SGMS2MEN1KMT2A
SCHEMBL1317041 0.84 HDAC1 (0.43) KIFC1HDAC1KDM4EALDH1A1CYP1A2
SCHEMBL1315346 0.83 HDAC1 (0.42) KIFC1HDAC1KDM4EALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 — — US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 — — US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 KIFC1 4197/4885HDAC1 73/4885KDM4E 1141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback