Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.52 |
| ▸ | MAP2 | P11137 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174707 | 0.90 | AKR1C3 (0.59) | AKR1C3MEN1KMT2APADI4ALDH1A1 | |
| SCHEMBL13173668 | 0.88 | AKR1C3 (0.58) | AKR1C3MAP2MEN1KMT2APADI4 | |
| SCHEMBL13173677 | 0.86 | AKR1C3 (0.50) | AKR1C3MAP2MEN1KMT2AALDH1A1 | |
| SCHEMBL13174673 | 0.85 | AKR1C3 (0.55) | AKR1C3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13174669 | 0.77 | AKR1C3 (0.61) | AKR1C3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11981464 | 0.76 | AKR1C3 (0.60) | AKR1C3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3106296 | 0.75 | AKR1C3 (0.66) | AKR1C3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3106490 | 0.75 | AKR1C3 (0.78) | AKR1C3MEN1KMT2A | |
| SCHEMBL13174667 | 0.73 | AKR1C3 (0.57) | AKR1C3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13173678 | 0.73 | PTGS2 (0.56) | AKR1C3MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101127-A1 | INDOLE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |