Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627663 | 0.82 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL18361548 | 0.81 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL30853079 | 0.78 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL364693 | 0.77 | GABRA1 (0.50) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL31155959 | 0.77 | GABRA1 (0.50) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL28383990 | 0.76 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| Methane SCHEMBL10700573 | 0.76 | GABRA1 (0.48) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL27763192 | 0.72 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL11670559 | 0.70 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL1333769 | 0.69 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1METAP2METAP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770132-B1 | NEW STREPTOGRAMINES | AVENTIS PHARMA SA (FR) | 2010-09-08 | — | — | EP | disclosed |