Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13178298 | 1.00 | TDP1 (0.34) | TDP1ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL13178301 | 1.00 | TDP1 (0.34) | TDP1ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL14855938 | 0.83 | ALDH1A1 (0.33) | TDP1ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL14855937 | 0.83 | ALDH1A1 (0.33) | TDP1ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL18570060 | 0.79 | MME (0.35) | TDP1HSD17B10KDM4ETSHRELANE | |
| SCHEMBL8097900 | 0.76 | ALDH1A1 (0.38) | TDP1ALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL14915112 | 0.72 | RARA (0.35) | TDP1ALDH1A1 | |
| SCHEMBL14855832 | 0.72 | RARA (0.35) | TDP1ALDH1A1 | |
| SCHEMBL1728192 | 0.68 | ALDH1A1 (0.37) | TDP1ALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL11618596 | 0.66 | ALDH1A1 (0.50) | TDP1ALDH1A1HSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501819-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-09-15 | — | — | EP | disclosed |