Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.43 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13137406 | 0.83 | CTSS (0.54) | CTSSCTSKALDH1A1KDM4EHPGD | |
| SCHEMBL342937 | 0.76 | LMNA (0.46) | ALDH1A1HDAC1HDAC6RECQLMAN2A1 | |
| SCHEMBL11378089 | 0.74 | LMNA (0.55) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL2117209 | 0.74 | LMNA (0.62) | ALDH1A1KDM4ELMNANPSR1MEN1 | |
| SCHEMBL1059560 | 0.72 | LMNA (0.56) | ALDH1A1MAN2A1MAN1B1LMNANPSR1 | |
| SCHEMBL805150 | 0.71 | LMNA (0.45) | ALDH1A1KDM4EHPGDHSD17B10MAN2A1 | |
| SCHEMBL13900616 | 0.71 | LMNA (0.51) | ALDH1A1RECQLLMNANPSR1MEN1 | |
| SCHEMBL9903332 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL16109508 | 0.69 | HDAC1 (0.62) | ALDH1A1HDAC1HDAC6LMNANPSR1 | |
| SCHEMBL3836681 | 0.69 | LMNA (0.72) | ALDH1A1HPGDHSD17B10HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222548-A1 | METHOD FOR PRODUCING CONDENSATION PRODUCTS FROM N-SUBSTITUTED GLYCINE DERIVATIVES(PEPTOIDS) BY SEQUENTIAL UGI-MULTICOMPONENT REACTIONS | WESSJOHANN LUDGER | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222548-A1 | METHOD FOR PRODUCING CONDENSATION PRODUCTS FROM N-SUBSTITUTED GLYCINE DERIVATIVES(PEPTOIDS) BY SEQUENTIAL UGI-MULTICOMPONENT REACTIONS | QPCT, GMPS, GMNN | CTSS 1687/4885CTSK 1428/4885ALDH1A1 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.