SCHEMBL131814

SCHEMBL131814

O=NNc1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.45
NPC1 O15118 4/20 0.45
HTT P42858 3/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 2/20 0.45
KDM1A O60341 1/20 0.42
KMT2A Q03164 5/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 4/20 0.41
KDM4E B2RXH2 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
CXCR2 P25025 2/20 0.41
RAB9A P51151 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4A O75164 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MMP9 P14780 2/20 0.41
RECQL P46063 2/20 0.41
CA12 O43570 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30393394 1.00 GAA (0.45) GAANPC1HTTLMNATP53
SCHEMBL30167903 0.82 ALDH1A1 (0.38) GAANPC1HTTLMNAKMT2A
SCHEMBL4897311 0.82 ALDH1A1 (0.38) GAANPC1HTTLMNAKMT2A
SCHEMBL18035433 0.71 MDM4 (0.44) HTTTP53MAPTRAB9AALDH1A1
SCHEMBL27325123 0.71 KMT2A (0.42) GAANPC1HTTLMNAKMT2A
SCHEMBL8346131 0.71 NPC1 (0.50) GAANPC1HTTLMNAKMT2A
SCHEMBL4363328 0.71 ALDH1A1 (0.57) GAANPC1LMNAKMT2AMAPT
SCHEMBL20489078 0.71 RAB9A (0.38) GAANPC1HTTLMNATP53
SCHEMBL11648181 0.71 NPC1 (0.53) GAANPC1HTTLMNATP53
SCHEMBL304891 0.71 CXCR2 (0.54) GAANPC1HTTLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6969613-B1 Method for determination of hydrogen sulfide or sulfide ion and method for determination of specific substance utilizing said method DAIICHI PURE CHEMICALS CO., LTD. (JP) 2005-11-29 US claimed
EP-1143244-B1 METHOD FOR DETERMINATION OF HYDROGEN SULFIDE OR SULFIDE ION AND METHOD FOR DETERMINATION OF SPECIFIC SUBSTANCE UTILIZING SAID METHOD DAIICHI PURE CHEMICALS CO LTD (JP) 2005-03-02 EP claimed
US-20030224421-A1 New oxazine dyes and their use as fluorescent markers HERRMANN RUPERT (DE) 2003-12-04 US claimed
EP-1143244-A1 METHOD FOR DETERMINATION OF HYDROGEN SULFIDE OR SULFIDE ION AND METHOD FOR DETERMINATION OF SPECIFIC SUBSTANCE UTILIZING SAID METHOD DAIICHI PURE CHEMICALS CO., LTD. (JP) 2001-10-10 EP claimed
EP-0747447-B1 Novel oxazine dyes and their use as fluorescent label ROCHE DIAGNOSTICS GMBH (DE) 2001-08-16 EP claimed
JP-9003343-A None JP disclosed
JP-60091265-A None JP disclosed
CN-117362260-B Photosensitizer containing NO donor structure and preparation method and antibacterial application thereof 中国药科大学 2025-11-21 CN disclosed
US-20240415115-A1 ANTIMICROBIAL PHOTOACTIVE NANOFIBROUS POLYMER MATERIAL LAM-X a.s. (CZ) 2024-12-19 US disclosed
CN-117362260-A Photosensitizer containing NO donor structure and preparation method and antibacterial application thereof 中国药科大学 2024-01-09 CN disclosed
CN-117362260-A Photosensitizer containing NO donor structure and preparation method and antibacterial application thereof 中国药科大学 2024-01-09 CN disclosed
WO-2023088507-A1 ANTIMICROBIAL PHOTOACTIVE NANOFIBROUS POLYMER MATERIAL LAM-X a.s. (CZ) 2023-05-25 WO disclosed
EP-1275517-A1 OPTICAL RECORDING MEDIUM MITSUBISHI CHEMICAL CORPORATION (JP) 2003-01-15 EP disclosed
US-6503995-B2 Hydrosilation KANEKA CORPORATION (JP) 2003-01-07 US disclosed
US-20020051941-A1 Optical recording medium MITSUBISHI CHEMICAL CORPORATION (JP) 2002-05-02 US disclosed
US-20020013427-A1 Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers KANEKA CORPORATION (JP) 2002-01-31 US disclosed
EP-1146062-A1 Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers Kaneka Corporation (JP) 2001-10-17 EP disclosed
EP-1143244-A1 METHOD FOR DETERMINATION OF HYDROGEN SULFIDE OR SULFIDE ION AND METHOD FOR DETERMINATION OF SPECIFIC SUBSTANCE UTILIZING SAID METHOD DAIICHI PURE CHEMICALS CO., LTD. (JP) 2001-10-10 EP disclosed
JP-H093343-A NOVEL OXAZINE DYE AND ITS USE AS FLUORESCENT MARKER BOEHRINGER MANNHEIM GMBH 1997-01-07 JP disclosed
JP-S6091265-A MEASUREMENT OF IRON IN SERUM MITSUBISHI CHEM IND LTD 1985-05-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030224421-A1 New oxazine dyes and their use as fluorescent markers HRH4, HCAR1, C9 GAA 4551/4885NPC1 3252/4885HTT 2365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.