SCHEMBL131820

SCHEMBL131820

C(=C/c1ccc2c(/C=C/c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc3cccc4ccc1c2c43)\c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.44
RELA Q04206 2/20 0.37
CHAT P28329 2/20 0.37
CYP1A2 P05177 2/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
PTGES O14684 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NQO2 P16083 1/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
KMT2A Q03164 2/20 0.35
RXFP1 Q9HBX9 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131821 1.00 APP (0.44) APPRELACHATCYP1A2ERBB2
SCHEMBL14570751 0.92 APP (0.48) APPRELACHATCYP1A2ERBB2
SCHEMBL455790 0.92 APP (0.48) APPRELACHATCYP1A2ERBB2
SCHEMBL455791 0.92 APP (0.48) APPRELACHATCYP1A2ERBB2
SCHEMBL8927220 0.91 APP (0.47) APPRELACHATCYP1A2ERBB2
SCHEMBL10050180 0.86 APP (0.46) APPRELACHATCYP1A2ALDH1A1
SCHEMBL14570748 0.84 APP (0.40) APPRELACYP1A2ERBB2FYN
SCHEMBL12659576 0.83 RELA (0.46) APPRELACYP1A2ERBB2FYN
SCHEMBL14570746 0.83 TRPA1 (0.47) APPRELACYP1A2NQO2KDM4E
SCHEMBL14570749 0.82 APP (0.40) APPRELACHATCYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521125-B1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 US disclosed
US-20050266331-A1 Electrophotographic photoconductor, electrophotography, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH COMPANY, LTD. (JP) 2005-12-01 US disclosed
EP-1521125-A1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound Ricoh Company (JP) 2005-04-06 EP disclosed