Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHAT | P28329 | 2/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455791 | 1.00 | APP (0.48) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL455790 | 1.00 | APP (0.48) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL8927220 | 0.99 | APP (0.47) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL10050180 | 0.93 | APP (0.46) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL131820 | 0.92 | APP (0.44) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL131821 | 0.92 | APP (0.44) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL14570748 | 0.92 | APP (0.40) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL14570746 | 0.90 | TRPA1 (0.47) | APPCYP1A2NQO2KDM4ERAB9A | |
| SCHEMBL462099 | 0.89 | APP (0.40) | APPALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL462098 | 0.89 | APP (0.40) | APPALDH1A1CYP1A2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186490-B1 | Photosensitive material, electrophotographic photoreceptor using the material, and electrophotographic image forming method and apparatus using the photoreceptor | RICOH COMPANY, LTD. (JP) | 2007-03-06 | — | — | US | disclosed |