Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.35 |
| ▸ | NOS2 | P35228 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14441606 | 0.78 | CYP1A2 (0.38) | NOS1NOS2CYP1A2NOS3TP53 | |
| SCHEMBL9706580 | 0.76 | CYP1A2 (0.38) | CYP1A2TP53TLR4NFKB1NFKB2 | |
| SCHEMBL2693722 | 0.75 | CYP1A2 (0.50) | NOS1NOS2CYP1A2TP53TLR4 | |
| SCHEMBL6526063 | 0.75 | CYP1A2 (0.50) | NOS1NOS2CYP1A2TP53TLR4 | |
| SCHEMBL4548488 | 0.73 | NOS1 (0.36) | NOS1NOS2CYP1A2NOS3ALDH1A1 | |
| SCHEMBL5027240 | 0.73 | TLR4 (0.38) | CYP1A2TLR4ALDH1A1POLBL3MBTL1 | |
| SCHEMBL5027232 | 0.73 | TLR4 (0.38) | CYP1A2TLR4ALDH1A1POLBL3MBTL1 | |
| SCHEMBL9469634 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL9470587 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL9470580 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097479-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2010-09-02 | — | — | WO | disclosed |