Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091362 | 0.78 | TMEM97 (0.64) | TAAR1L3MBTL1TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL3063318 | 0.78 | TAAR1 (0.64) | TAAR1L3MBTL1TMEM97SIGMAR1GPR84 | |
| Hydrochloric Acid SCHEMBL8576229 | 0.76 | TMEM97 (0.61) | TAAR1L3MBTL1TMEM97SIGMAR1ALDH1A1 | |
| Bromide SCHEMBL27562319 | 0.76 | TMEM97 (0.61) | TAAR1L3MBTL1TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL21340678 | 0.76 | SIGMAR1 (0.40) | TAAR1TMEM97SIGMAR1 | |
| SCHEMBL23664561 | 0.76 | IDO1 (0.40) | TAAR1L3MBTL1TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL6546733 | 0.76 | TAAR1 (0.68) | TAAR1L3MBTL1LPLLIPGGPR84 | |
| SCHEMBL23590401 | 0.76 | SMN1; SMN2 (0.62) | TAAR1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL1815007 | 0.75 | LMNA (0.58) | TAAR1L3MBTL1SIGMAR1CYP2C9ALDH1A1 | |
| Bromide SCHEMBL27615440 | 0.74 | TMEM97 (0.59) | TAAR1L3MBTL1TMEM97SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228065-A2 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2010-09-15 | — | — | EP | disclosed |