Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.44 |
| ▸ | TET3 | O43151 | 3/20 | 0.44 |
| ▸ | FBXL19 | Q6PCT2 | 3/20 | 0.44 |
| ▸ | CXXC5 | Q7LFL8 | 3/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
| ▸ | CXXC4 | Q9H2H0 | 3/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.44 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468360 | 0.89 | GRIN2B (0.48) | ALDH1A1KMT2AOPRL1TSHRCHRM5 | |
| SCHEMBL2468358 | 0.89 | GRIN2B (0.48) | ALDH1A1KMT2AOPRL1TSHRCHRM5 | |
| SCHEMBL2467182 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KMT2AOPRL1TET3FBXL19 | |
| SCHEMBL2467179 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KMT2AOPRL1TET3FBXL19 | |
| SCHEMBL2468363 | 0.82 | CHRM5 (0.58) | ALDH1A1KMT2AOPRL1TET3FBXL19 | |
| SCHEMBL2468362 | 0.82 | CHRM5 (0.58) | ALDH1A1KMT2AOPRL1TET3FBXL19 | |
| SCHEMBL2472772 | 0.81 | KMT2A (0.48) | ALDH1A1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL2472775 | 0.81 | KMT2A (0.48) | ALDH1A1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL2473530 | 0.80 | CHRM5 (0.53) | ALDH1A1KMT2AOPRL1TET3FBXL19 | |
| SCHEMBL13182920 | 0.80 | CHRM5 (0.53) | ALDH1A1KMT2AOPRL1TET3FBXL19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228065-A2 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2010-09-15 | — | — | EP | disclosed |