Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451377 | 0.85 | FLT3 (0.80) | FLT3L3MBTL1MAPTTP53KDM4E | |
| SCHEMBL3397527 | 0.84 | FLT3 (0.71) | FLT3L3MBTL1MAPTTP53KDM4E | |
| SCHEMBL13183018 | 0.81 | ALDH1A1 (0.57) | FLT3L3MBTL1MAPTKDM4EMAPK1 | |
| SCHEMBL13183040 | 0.80 | SMN1; SMN2 (0.68) | FLT3MAPTTP53KDM4ENPC1 | |
| SCHEMBL8290601 | 0.79 | L3MBTL1 (0.72) | FLT3L3MBTL1MAPTTP53KDM4E | |
| SCHEMBL8290673 | 0.78 | FLT3 (0.78) | FLT3L3MBTL1MAPTTP53KDM4E | |
| SCHEMBL8289506 | 0.77 | ALDH1A1 (0.74) | FLT3L3MBTL1MAPTKDM4EMAPK1 | |
| SCHEMBL34468495 | 0.75 | FLT3 (0.66) | FLT3L3MBTL1MAPTTP53KDM4E | |
| SCHEMBL5458397 | 0.75 | ALDH1A1 (0.79) | FLT3L3MBTL1MAPTKDM4EMAPK1 | |
| SCHEMBL8289835 | 0.74 | FLT3 (0.71) | FLT3L3MBTL1MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222381-A1 | Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors | VANKAYALAPATI HARIPRASAD | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222381-A1 | Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors | DNMT3B, DNMT1, DNMT3L | FLT3 2295/4885L3MBTL1 675/4885MAPT 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.