Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | TP53 | P04637 | 5/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468545 | 0.89 | POLB (0.83) | FLT3MAPTTP53RXFP1ALDH1A1 | |
| SCHEMBL34468612 | 0.89 | MAPT (0.78) | FLT3MAPTTP53RXFP1ALDH1A1 | |
| SCHEMBL8288731 | 0.88 | MAPT (0.74) | FLT3MAPTTP53ALDH1A1POLB | |
| SCHEMBL34468593 | 0.82 | POLB (0.85) | FLT3MAPTTP53ALDH1A1POLB | |
| SCHEMBL8289522 | 0.81 | TP53 (0.75) | FLT3MAPTTP53ALDH1A1L3MBTL1 | |
| SCHEMBL34468552 | 0.81 | POLB (0.83) | FLT3MAPTTP53RXFP1ALDH1A1 | |
| SCHEMBL5805621 | 0.81 | ALDH1A1 (0.72) | MAPTALDH1A1L3MBTL1POLBKDM4E | |
| SCHEMBL8289622 | 0.81 | POLB (0.76) | MAPTTP53ALDH1A1POLBTHRB | |
| SCHEMBL3911862 | 0.81 | GLO1 (0.83) | FLT3MAPTTP53ALDH1A1L3MBTL1 | |
| SCHEMBL34468588 | 0.80 | POLB (0.82) | FLT3MAPTTP53RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |