Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459959 | 0.87 | TOP1 (0.53) | TERTTOP1 | |
| SCHEMBL224502 | 0.86 | TERT (0.39) | TERTALDH1A1HPGDTOP1CYP3A4 | |
| SCHEMBL28296392 | 0.85 | TERT (0.38) | TERTALDH1A1HPGDTOP1CYP3A4 | |
| SCHEMBL24186971 | 0.84 | CYP11B1 (0.50) | CYP11B1CYP11B2KDM4EMEN1NPC1 | |
| SCHEMBL3459339 | 0.83 | TOP1 (0.34) | TERTTOP1 | |
| SCHEMBL185112 | 0.82 | TERT (0.54) | TERTKDM4EALDH1A1TOP1CYP19A1 | |
| SCHEMBL29501072 | 0.82 | TERT (0.54) | TERTKDM4EALDH1A1TOP1CYP19A1 | |
| SCHEMBL13183881 | 0.81 | TOP1 (0.47) | TERTTOP1 | |
| SCHEMBL30385992 | 0.81 | TERT (0.52) | TERTKDM4EALDH1A1TOP1CYP19A1 | |
| SCHEMBL21808804 | 0.81 | TERT (0.52) | TERTKDM4EALDH1A1TOP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230242-B1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | JOHANNES KEPLER UNI (AT) | 2013-08-14 | — | — | EP | disclosed |
| EP-2230242-A1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | Johannes Kepler Universität (AT) | 2010-09-22 | — | — | EP | disclosed |