Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | TERT | O14746 | 4/20 | 0.41 |
| ▸ | CYCS | P99999 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224502 | 0.89 | TERT (0.39) | TOP1TERTCYCSENPP2 | |
| SCHEMBL3459223 | 0.89 | TOP1 (0.46) | TOP1TERTCYCSENPP2 | |
| SCHEMBL13183881 | 0.89 | TOP1 (0.47) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL28296392 | 0.88 | TERT (0.38) | TOP1TERTCYCSENPP2 | |
| SCHEMBL13183875 | 0.87 | TERT (0.40) | TOP1TERT | |
| Hydrochloric Acid SCHEMBL3459214 | 0.85 | TERT (0.61) | TOP1TERTCYCSENPP2 | |
| SCHEMBL3459339 | 0.82 | TOP1 (0.34) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL29961137 | 0.79 | TOP1 (0.78) | TOP1TERTCYCSENPP2 | |
| SCHEMBL245937 | 0.79 | TOP1 (0.78) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL2101556 | 0.78 | TOP1 (0.76) | TOP1TERTCYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230242-B1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | JOHANNES KEPLER UNI (AT) | 2013-08-14 | — | — | EP | disclosed |
| EP-2230242-A1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | Johannes Kepler Universität (AT) | 2010-09-22 | — | — | EP | disclosed |
| EP-2230242-A1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | Johannes Kepler Universität (AT) | 2010-09-22 | — | — | EP | disclosed |