SCHEMBL1318436

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12117854	0.88	ACLY (0.48)	MEN1KMT2ACA12CA1CA2
	SCHEMBL14428246	0.86	HDAC1 (0.57)	MEN1KMT2AHDAC1ACLYALDH1A1
	SCHEMBL4835334	0.85	TSHR (0.58)	MEN1KMT2AHDAC1TP53SMN1; SMN2
	SCHEMBL2271167	0.83	KDM4E (0.64)	MEN1KMT2AHDAC1ACLYALDH1A1
	SCHEMBL1316971	0.82	LRRK2 (0.50)	MEN1KMT2AACLYALDH1A1SMN1; SMN2
	SCHEMBL1316473	0.81	HDAC1 (0.51)	MEN1KMT2AHDAC1ACLYHDAC2
	SCHEMBL1317238	0.81	ACLY (0.60)	MEN1KMT2AHDAC1ACLYALDH1A1
	SCHEMBL12121545	0.81	SMN1; SMN2 (0.47)	ACLYALDH1A1PPARGNCOA2NCOA1
	SCHEMBL12117881	0.80	KDM1A (0.44)	MEN1KMT2AHDAC1ACLYALDH1A1
	SCHEMBL12117706	0.80	KMT2A (0.56)	MEN1KMT2AACLYALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.