Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186469 | 0.87 | CYP1A2 (0.64) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL13186458 | 0.84 | CYP1A2 (0.73) | MAPTMEN1KMT2ALMNAGPR55 | |
| SCHEMBL12010901 | 0.83 | NPC1 (0.66) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13186804 | 0.78 | MEN1 (0.85) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL15726678 | 0.78 | NPC1 (0.56) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL16430359 | 0.78 | MEN1 (0.64) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL13186809 | 0.76 | MEN1 (0.72) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL11598524 | 0.75 | MAPT (0.73) | MAPTMEN1KMT2ALMNAGPR55 | |
| SCHEMBL5331526 | 0.75 | MMP13 (0.74) | MEN1KMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL11172199 | 0.75 | POLB (0.77) | MAPTMEN1KMT2AGPR55ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100248371-A1 | METHODS AND COMPOSITIONS FOR MODULATING RAD51 AND HOMOLOGOUS RECOMBINATION | UNIVERSITY OF CHICAGO (US) | 2010-09-30 | — | — | US | disclosed |