Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TCF4 | P15884 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430155 | 0.91 | KMT2A (0.77) | MEN1KMT2ATCF4CTNNB1CYP19A1 | |
| SCHEMBL17331340 | 0.83 | KEAP1 (0.57) | MEN1KMT2ATCF4CTNNB1RAB9A | |
| SCHEMBL12010901 | 0.83 | NPC1 (0.66) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL17331331 | 0.82 | LMNA (0.60) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16430604 | 0.82 | TCF4 (0.62) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL15952823 | 0.80 | TUBB (0.61) | MEN1KMT2ASMN1; SMN2RAB9AMAPT | |
| SCHEMBL16430711 | 0.80 | TCF4 (0.66) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL17347407 | 0.79 | LMNA (0.62) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL16430506 | 0.79 | TCF4 (0.67) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL5331977 | 0.78 | MMP13 (0.76) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015016293-A1 | (BENZENESULFONYLAMINO)BENZAMIDE DERIVATIVE, AND SHIP2 INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | 国立大学法人 富山大学 (JP) | 2015-02-05 | — | — | WO | disclosed |