SCHEMBL1318665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1317810	0.83	AURKA (0.63)	LMNAKMT2AKDM4EALDH1A1HSD17B10
	SCHEMBL1318722	0.83	AURKA (0.63)	LMNAKMT2AKDM4EALDH1A1HSD17B10
	SCHEMBL3720386	0.83	AURKA (0.63)	LMNAKMT2AKDM4EALDH1A1HSD17B10
	SCHEMBL1317503	0.83	PDPK1 (0.61)	LMNAALDH1A1HSD17B10PDPK1ROCK1
	SCHEMBL21540812	0.81	GPBAR1 (0.51)	KMT2AKDM4EMEN1ALDH1A1HSD17B10
	SCHEMBL27738442	0.79	LMNA (0.53)	LMNAKMT2AMEN1CYP1A2CYP2D6
	SCHEMBL4000534	0.79	KDM4E (0.51)	LMNAKMT2AKDM4EMEN1ALDH1A1
	SCHEMBL23582548	0.78	HRH3 (0.52)	KMT2AKDM4EMEN1ALDH1A1HSD17B10
	SCHEMBL23582547	0.78	HRH3 (0.52)	KMT2AKDM4EMEN1ALDH1A1HSD17B10
	SCHEMBL1318206	0.77	LMNA (0.48)	LMNAKMT2ACYP1A2CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.