Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716625 | 0.91 | TLR7 (0.41) | SYK | |
| SCHEMBL13188373 | 0.89 | HDAC1 (0.46) | MAPK14ALKACACB | |
| SCHEMBL13188620 | 0.86 | KMO (0.47) | MAPK14ALKACACBBCHEMAOA | |
| SCHEMBL3716614 | 0.85 | HDAC1 (0.49) | ACACB | |
| SCHEMBL3710611 | 0.83 | ACACB (0.47) | ACACBPIK3CASYKBCHEMAOA | |
| SCHEMBL3709560 | 0.82 | KMO (0.50) | ACACBBCHEMAOAACHEMAOB | |
| SCHEMBL3713800 | 0.79 | HDAC1 (0.44) | — | |
| SCHEMBL3715177 | 0.78 | TLR7 (0.44) | PIK3CA | |
| SCHEMBL3713860 | 0.77 | MAPK14 (0.41) | MAPK14ALKACACB | |
| SCHEMBL13187744 | 0.77 | HDAC1 (0.51) | MAPK14ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |