Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188373 | 0.96 | HDAC1 (0.46) | HDAC1KDM1AACACB | |
| SCHEMBL3713800 | 0.92 | HDAC1 (0.44) | HDAC1MMP2MMP8MMP13 | |
| SCHEMBL3709560 | 0.90 | KMO (0.50) | ACACB | |
| SCHEMBL3710611 | 0.90 | ACACB (0.47) | HDAC1KDM1AACACB | |
| SCHEMBL13188620 | 0.86 | KMO (0.47) | ACACB | |
| SCHEMBL13187751 | 0.85 | MAPK14 (0.42) | ACACB | |
| SCHEMBL13187705 | 0.84 | HDAC1 (0.55) | HDAC1KDM1AACACBMMP2MMP8 | |
| SCHEMBL3716618 | 0.84 | MMP2 (0.48) | HDAC1MMP2MMP8MMP13HDAC3 | |
| SCHEMBL3715177 | 0.83 | TLR7 (0.44) | — | |
| SCHEMBL13187744 | 0.81 | HDAC1 (0.51) | HDAC1KDM1AHDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |