Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726822 | 0.76 | MAPT (0.37) | — | |
| SCHEMBL31166717 | 0.67 | ERN1 (0.40) | — | |
| SCHEMBL17183930 | 0.66 | AKT1 (0.35) | PAX8 | |
| SCHEMBL27078467 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL9847278 | 0.65 | PAX8 (0.33) | PAX8 | |
| SCHEMBL30369278 | 0.65 | AAK1 (0.37) | — | |
| SCHEMBL28743743 | 0.65 | GABRG2 (0.35) | — | |
| SCHEMBL23340561 | 0.64 | SSTR4 (0.30) | — | |
| SCHEMBL30759332 | 0.64 | USP30 (0.32) | — | |
| SCHEMBL28612868 | 0.64 | PTPRC (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403860-B1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE AS HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |
| WO-2010101967-A2 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-09-10 | — | — | WO | disclosed |