Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NPY1R | P25929 | 1/20 | 0.62 |
| ▸ | NPY2R | P49146 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | FADS1 | O60427 | 1/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 7/20 | 0.59 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771752 | 0.88 | P2RX1 (0.70) | P2RX1MAPTKDM4EHTTLMNA | |
| SCHEMBL24460172 | 0.88 | P2RX1 (0.70) | P2RX1MAPTKDM4EHTTLMNA | |
| SCHEMBL14363379 | 0.87 | LMNA (0.60) | P2RX1MAPTKDM4EHTTLMNA | |
| SCHEMBL16147503 | 0.86 | P2RX1 (0.66) | P2RX1MAPTKDM4EHTTLMNA | |
| SCHEMBL13812835 | 0.85 | MAPT (0.70) | P2RX1MAPTKDM4ENPC1POLB | |
| SCHEMBL18290068 | 0.81 | P2RX1 (0.80) | P2RX1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL13812587 | 0.80 | MAPT (0.56) | P2RX1MAPTKDM4EHTTLMNA | |
| SCHEMBL13772243 | 0.80 | KCNMA1 (0.59) | P2RX1MAPTKDM4EHTTLMNA | |
| SCHEMBL5464135 | 0.80 | RAB9A (0.50) | P2RX1MAPTKDM4EHTTLMNA | |
| SCHEMBL330394 | 0.79 | TMPRSS4 (0.79) | P2RX1MAPTKDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101648-A1 | GLUTAMATE RECEPTOR MODULATORS AND THERAPEUTIC AGENTS | WOOD RICHARD D (US) | 2010-09-10 | — | — | WO | disclosed |