Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190242 | 0.86 | HPGD (0.63) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL3455703 | 0.85 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL13190087 | 0.83 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL13190086 | 0.82 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL15385126 | 0.82 | NPC1 (0.76) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL3090181 | 0.77 | NPC1 (0.69) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL13190241 | 0.74 | PYGL (0.43) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL13190084 | 0.74 | POLB (0.41) | RAB9ANPC1SMN1; SMN2HPGDGAA | |
| SCHEMBL11688371 | 0.72 | NPC1 (0.67) | RAB9ANPC1SMN1; SMN2HPGDCA12 | |
| SCHEMBL15385121 | 0.72 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2010100249-A1 | 3H-IMIDAZO [4, 5 -C] PYRIDINE- 6 -CARBOXAMIDES AS ANTI- INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |