Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296584 | 0.79 | PTPRC (0.45) | HSD17B10ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL31032281 | 0.78 | ALDH1A1 (0.47) | HSD17B10HSP90AA1ALDH1A1ALOX15HNF4A | |
| SCHEMBL569778 | 0.78 | ALDH1A1 (0.47) | HSD17B10HSP90AA1ALDH1A1ALOX15HNF4A | |
| SCHEMBL29950657 | 0.75 | ALDH1A1 (0.50) | HSD17B10HSP90AA1ALDH1A1ALOX15MAPT | |
| SCHEMBL5866455 | 0.75 | HSP90AA1 (0.62) | HSD17B10HSP90AA1ALDH1A1ALOX15HNF4A | |
| SCHEMBL15330692 | 0.75 | ALDH1A1 (0.50) | HSD17B10HSP90AA1ALDH1A1ALOX15MAPT | |
| SCHEMBL1658784 | 0.74 | PARP1 (0.47) | HSD17B10ALDH1A1ALOX15LMNAMAPT | |
| SCHEMBL1759573 | 0.72 | MRGPRX4 (0.51) | HSD17B10HSP90AA1ALDH1A1ALOX15HNF4A | |
| SCHEMBL11524733 | 0.72 | AKR1B1 (0.56) | HSP90AA1ALDH1A1ALOX15HNF4AL3MBTL1 | |
| SCHEMBL29769278 | 0.71 | CYP1A2 (0.63) | HSD17B10ALDH1A1ALOX15MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108651-A1 | SUBSTITUTED SPIRO-AMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2010-09-30 | — | — | WO | disclosed |