Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670579 | 0.85 | ALDH1A1 (0.40) | ALDH1A1ALOX15HPGDSMN1; SMN2POLB | |
| SCHEMBL671042 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2POLBGALR2 | |
| SCHEMBL13190097 | 0.78 | ALDH1A1 (0.43) | ALDH1A1ALOX15HPGDSMN1; SMN2POLB | |
| SCHEMBL15268117 | 0.78 | KMT2A (0.41) | ALDH1A1SMN1; SMN2LMNATSHRKDM4E | |
| SCHEMBL16448805 | 0.77 | ABCB1 (0.45) | ALDH1A1HPGDSMN1; SMN2LMNANPSR1 | |
| SCHEMBL1725466 | 0.77 | ALDH1A1 (0.45) | ALDH1A1ALOX15HPGDSMN1; SMN2LMNA | |
| SCHEMBL1672502 | 0.72 | GAA (0.48) | ALDH1A1ALOX15HPGDSMN1; SMN2LMNA | |
| SCHEMBL11951456 | 0.71 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MITFLMNATSHR | |
| SCHEMBL11962194 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDSMN1; SMN2HSP90AA1TSHR | |
| SCHEMBL27903410 | 0.71 | HNF4A (0.33) | ALDH1A1HPGDSMN1; SMN2POLBGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100249-A1 | 3H-IMIDAZO [4, 5 -C] PYRIDINE- 6 -CARBOXAMIDES AS ANTI- INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |