SCHEMBL670579

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11951456	0.87	ALDH1A1 (0.45)	ALDH1A1HSD17B10GAAMAPK1PTGER4
	SCHEMBL1725466	0.87	ALDH1A1 (0.45)	ALDH1A1HSD17B10GAAMAPK1DPP4
	SCHEMBL13190096	0.85	ALDH1A1 (0.37)	ALDH1A1HSD17B10GAADPP4KDM4E
	SCHEMBL671609	0.85	KDM4E (0.36)	ALDH1A1GAAKDM4ELMNAMAPT
	SCHEMBL11951408	0.85	PRKCI (0.40)	MAPTTSHR
	SCHEMBL671042	0.81	ALDH1A1 (0.53)	ALDH1A1GAAMAPK1PTGER4KDM4E
	SCHEMBL11962194	0.78	ALDH1A1 (0.40)	ALDH1A1HSD17B10GAAMAPK1DPP4
	SCHEMBL1964928	0.78	ALDH1A1 (0.46)	ALDH1A1HSD17B10GAAMAPK1PTGER4
	SCHEMBL1672502	0.77	GAA (0.48)	ALDH1A1HSD17B10GAAMAPK1CDC25B
	SCHEMBL671333	0.76	ALDH1A1 (0.49)	ALDH1A1HSD17B10KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.