Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176238 | 0.85 | CES2 (0.44) | CES1CES2TSHRALDH1A1 | |
| SCHEMBL8775440 | 0.81 | FFAR3 (0.42) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL18615545 | 0.80 | TDP1 (0.38) | FFAR3ALDH1A1 | |
| SCHEMBL6059836 | 0.76 | TSHR (0.36) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL14119539 | 0.76 | CA1 (0.41) | ALDH1A1 | |
| SCHEMBL762293 | 0.73 | — | — | |
| SCHEMBL14208300 | 0.68 | — | — | |
| SCHEMBL24680905 | 0.68 | GAA (0.45) | TSHRALDH1A1LMNA | |
| SCHEMBL9070666 | 0.67 | ALDH1A1 (0.35) | CES2TSHRALDH1A1LMNA | |
| SCHEMBL13317540 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010104406-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-09-16 | — | — | WO | disclosed |