Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191267 | 0.89 | BDKRB1 (0.35) | RAB9AALDH1A1APLNRBDKRB1PKM | |
| SCHEMBL13191602 | 0.89 | BDKRB1 (0.38) | P2RX7BDKRB1EPHX2 | |
| SCHEMBL13191647 | 0.89 | P2RX7 (0.37) | P2RX7BDKRB1EPHX2POLB | |
| SCHEMBL13191622 | 0.88 | EPHX2 (0.47) | P2RX7BDKRB1EPHX2MAPK1 | |
| SCHEMBL3722725 | 0.88 | L3MBTL1 (0.36) | RAB9ANPC1ALDH1A1P2RX7CYP1A2 | |
| SCHEMBL13191623 | 0.87 | EPHX2 (0.45) | RAB9AP2RX7BDKRB1EPHX2MAPK1 | |
| SCHEMBL13191624 | 0.87 | EPHX2 (0.40) | P2RX7BDKRB1EPHX2 | |
| SCHEMBL13191241 | 0.87 | BDKRB1 (0.37) | P2RX7BDKRB1EPHX2 | |
| SCHEMBL13191620 | 0.87 | BDKRB1 (0.41) | ALDH1A1P2RX7HPGDBDKRB1EPHX2 | |
| SCHEMBL3719007 | 0.86 | P2RX7 (0.37) | P2RX7BDKRB1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |