Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728615 | 0.79 | CA12 (0.40) | NR1H2NR1H3KDM4EMAPTPOLB | |
| SCHEMBL1319878 | 0.76 | CFD (0.45) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL6536425 | 0.75 | CA12 (0.42) | NR1H2NR1H3KDM4EMAPTPOLB | |
| SCHEMBL28058206 | 0.74 | TSHR (0.49) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL27962389 | 0.74 | HSD17B2 (0.49) | KDM4EMAPTPOLBCA12CA1 | |
| SCHEMBL2424121 | 0.73 | ELANE (0.39) | KDM4EPOLBTSHRHSD17B10TDP1 | |
| SCHEMBL27788214 | 0.70 | ALDH1A1 (0.42) | NR1H2NR1H3MAPTCA12CA1 | |
| SCHEMBL1355426 | 0.70 | KDM4E (0.39) | KDM4EMAPTPOLBTSHRCYP3A4 | |
| SCHEMBL27969884 | 0.69 | TSHR (0.32) | TSHRHSD17B10 | |
| SCHEMBL65777 | 0.69 | CFD (0.44) | KDM4ETSHRHSD17B10TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9937104-B2 | Nanostructured antibacterial and remineralizing dental bonding agents and dental bonding systems | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-04-10 | — | — | US | claimed |
| US-20170202752-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-07-20 | — | — | US | claimed |
| EP-3171849-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | The University of Maryland, Baltimore (US) | 2017-05-31 | — | — | EP | claimed |
| US-20170112723-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-04-27 | — | — | US | claimed |
| US-9554971-B2 | Nanostructured antibacterial and remineralizing dental bonding agents and dental bonding systems | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-01-31 | — | — | US | claimed |
| US-20160058675-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-03 | — | — | US | claimed |
| WO-2016015005-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-01-28 | — | — | WO | claimed |
| EP-2811966-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | University of Maryland (US) | 2014-12-17 | — | — | EP | claimed |
| WO-2013119901-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | UNIVERSITY OF MARYLAND (US) | 2013-08-15 | — | — | WO | claimed |
| WO-2013057519-A1 | DENTAL ADHESIVE SYSTEMS | KING'S COLLEGE LONDON (GB) | 2013-04-25 | — | — | WO | claimed |
| EP-2571479-A2 | DENTAL COMPOSITIONS | Levin, Leana (US) | 2013-03-27 | — | — | EP | claimed |
| US-20110275035-A1 | DENTAL COMPOSITIONS | DENTSPLY INTERNATIONAL INC. (US) | 2011-11-10 | — | — | US | claimed |
| WO-2011139936-A2 | DENTAL COMPOSITIONS | LEVIN, LEANA (US) | 2011-11-10 | — | — | WO | claimed |
| US-9937104-B2 | Nanostructured antibacterial and remineralizing dental bonding agents and dental bonding systems | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170202752-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-07-20 | — | — | US | disclosed |
| EP-3171849-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | The University of Maryland, Baltimore (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-2571479-A2 | DENTAL COMPOSITIONS | Levin, Leana (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2012146832-A2 | A METHOD FOR IMPROVING PENETRATION OR LONG TERM ADHESION OF COMPOSITIONS TO DENTAL TISSUES AND COMPOSITIONS USABLE IN SAID METHOD | OULUN YLIOPISTO (FI) | 2012-11-01 | — | — | WO | disclosed |
| US-20110275035-A1 | DENTAL COMPOSITIONS | DENTSPLY INTERNATIONAL INC. (US) | 2011-11-10 | — | — | US | disclosed |
| WO-2011139936-A2 | DENTAL COMPOSITIONS | LEVIN, LEANA (US) | 2011-11-10 | — | — | WO | disclosed |