Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPA | Q15257 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728615 | 0.81 | CA12 (0.40) | CFDMAPTALDH1A1GAAKDM4E | |
| SCHEMBL6536425 | 0.77 | CA12 (0.42) | MAPTALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL1319507 | 0.76 | NR1H2 (0.37) | MAPTALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL28058206 | 0.73 | TSHR (0.49) | MAPTALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL27962389 | 0.71 | HSD17B2 (0.49) | HTTMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL15495837 | 0.71 | CA12 (0.59) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL27818668 | 0.70 | ALDH1A1 (0.43) | HTTMAPTALDH1A1GAAKDM4E | |
| SCHEMBL27488935 | 0.70 | ELANE (0.40) | CFDMAPTALDH1A1GAAKDM4E | |
| SCHEMBL339060 | 0.69 | PTPN1 (0.48) | PTPN11PTPN1PTPRCPTPRFPTPN2 | |
| SCHEMBL3009969 | 0.69 | TSHR (0.61) | MAPTALDH1A1GAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571479-A2 | DENTAL COMPOSITIONS | Levin, Leana (US) | 2013-03-27 | — | — | EP | claimed |
| US-20110275035-A1 | DENTAL COMPOSITIONS | DENTSPLY INTERNATIONAL INC. (US) | 2011-11-10 | — | — | US | claimed |
| WO-2011139936-A2 | DENTAL COMPOSITIONS | LEVIN, LEANA (US) | 2011-11-10 | — | — | WO | claimed |
| US-10813849-B2 | Rechargeable calcium phosphate-containing dental materials | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190290550-A1 | METFORMIN-CONTAINING DENTAL MATERIALS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2019-09-26 | — | — | US | disclosed |
| US-9452112-B2 | Dental compositions | DENTSPLY INTERNATIONAL INC. (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160228335-A1 | RECHARGEABLE CALCIUM PHOSPHATE-CONTAINING DENTAL MATERIALS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-08-11 | — | — | US | disclosed |
| EP-2571479-A2 | DENTAL COMPOSITIONS | Levin, Leana (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20110275035-A1 | DENTAL COMPOSITIONS | DENTSPLY INTERNATIONAL INC. (US) | 2011-11-10 | — | — | US | disclosed |
| WO-2011139936-A2 | DENTAL COMPOSITIONS | LEVIN, LEANA (US) | 2011-11-10 | — | — | WO | disclosed |