Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780358 | 0.83 | CNR2 (0.39) | POLBALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL2783319 | 0.82 | POLB (0.40) | POLBALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL2781670 | 0.82 | ALDH1A1 (0.41) | POLBALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL2781258 | 0.81 | POLB (0.44) | POLBALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL2781466 | 0.74 | ALDH1A1 (0.37) | POLBALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL2780477 | 0.74 | ALDH1A1 (0.37) | POLBALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL13274021 | 0.73 | ANPEP (0.39) | POLBALDH1A1ANPEP | |
| SCHEMBL13196436 | 0.71 | POLB (0.45) | POLBALDH1A1ANPEPL3MBTL1HTT | |
| SCHEMBL13196426 | 0.70 | ALDH1A1 (0.52) | POLBALDH1A1ANPEPL3MBTL1HTT | |
| SCHEMBL2783111 | 0.70 | POLB (0.48) | POLBALDH1A1ANPEPHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |