Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780892 | 0.92 | CNR2 (0.44) | POLBANPEPCNR2KDM4EPKM | |
| SCHEMBL2784556 | 0.88 | PKM (0.41) | POLBCNR2PKMTSHRALDH1A1 | |
| SCHEMBL2780358 | 0.88 | CNR2 (0.39) | POLBANPEPCNR2KDM4EPKM | |
| SCHEMBL13196442 | 0.88 | ALDH1A1 (0.41) | POLBANPEPCNR2KDM4EPKM | |
| SCHEMBL2780780 | 0.83 | PKM (0.38) | POLBANPEPCNR2PKMTSHR | |
| SCHEMBL13196449 | 0.83 | POLB (0.41) | POLBANPEPCNR2KDM4ETSHR | |
| SCHEMBL13196558 | 0.83 | NAMPT (0.39) | POLBCNR2HTT | |
| SCHEMBL13196451 | 0.82 | ALDH1A1 (0.39) | POLBANPEPCNR2PKMTSHR | |
| SCHEMBL2782395 | 0.81 | HTT (0.39) | POLBCNR2ALDH1A1LMNAHTT | |
| SCHEMBL13196575 | 0.80 | CNR2 (0.40) | POLBANPEPCNR2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |