Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781466 | 1.00 | ALDH1A1 (0.37) | ALDH1A1POLBANPEPARKDM4E | |
| SCHEMBL2780482 | 1.00 | ALDH1A1 (0.37) | ALDH1A1POLBANPEPARKDM4E | |
| SCHEMBL2783324 | 0.83 | ALDH1A1 (0.34) | ALDH1A1POLBANPEPARL3MBTL1 | |
| SCHEMBL13196497 | 0.83 | ALDH1A1 (0.34) | ALDH1A1POLBANPEPARL3MBTL1 | |
| SCHEMBL2781219 | 0.83 | ALDH1A1 (0.34) | ALDH1A1POLBANPEPARL3MBTL1 | |
| SCHEMBL13196437 | 0.82 | ALDH1A1 (0.43) | ALDH1A1POLBANPEPKDM4EL3MBTL1 | |
| SCHEMBL13196420 | 0.81 | POLB (0.37) | ALDH1A1POLBANPEPAR | |
| SCHEMBL2779726 | 0.79 | LMNA (0.48) | ALDH1A1ANPEPL3MBTL1TSHRLMNA | |
| SCHEMBL2781258 | 0.75 | POLB (0.44) | ALDH1A1POLBANPEPKDM4EL3MBTL1 | |
| SCHEMBL2781670 | 0.74 | ALDH1A1 (0.41) | ALDH1A1POLBANPEPKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |