Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779556 | 0.92 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| SCHEMBL7944637 | 0.80 | CYP11B2 (1.00) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| SCHEMBL31140124 | 0.78 | ADRA2A (0.74) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL31140107 | 0.78 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| SCHEMBL31140093 | 0.78 | ADRA2A (0.60) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| SCHEMBL31140125 | 0.75 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| SCHEMBL769064 | 0.75 | ADRA2A (0.67) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| Hydrochloric Acid SCHEMBL768967 | 0.74 | ADRA2A (0.66) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| SCHEMBL18826066 | 0.73 | CYP19A1 (0.54) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 | |
| SCHEMBL31140109 | 0.72 | ADRA2A (0.77) | ADRA2AADRA2BADRA2CCYP19A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766866-B2 | Deterrents for arthropods and marine organisms | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2020-09-08 | — | — | US | disclosed |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | 2019-09-26 | — | — | US | disclosed |
| US-7767667-B2 | Pesticidal heterocycles | FMC CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767667-B2 | Pesticidal heterocycles | FMC CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-7417057-B2 | Pesticidal heterocycles | BAYER CROPSCIENCE AG (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417057-B2 | Pesticidal heterocycles | BAYER CROPSCIENCE AG (DE) | 2008-08-26 | — | — | US | disclosed |
| CN-1068592-C | Imidazole derivatives having affinity for alpha 2 receptors activity | ORION YHTYMAE OY (FI) | 2001-07-18 | — | — | CN | disclosed |
| CN-1198741-A | Imidazole derivatives having affinity for alpha 2 receptor activity | ORION YHTYMAE OY (FI) | 1998-11-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766866-B2 | Deterrents for arthropods and marine organisms | ALG1, NISCH, ALG8 | ADRA2A 1749/4885ADRA2B 3315/4885ADRA2C 1733/4885 |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | DDT, CBR3, ACHE | ADRA2A 1935/4885ADRA2B 1213/4885ADRA2C 560/4885 |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | ALG1, NISCH, ALG8 | ADRA2A 1749/4885ADRA2B 3315/4885ADRA2C 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.