Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13196461 | 0.87 | PKM (0.38) | ALDH1A1PKMKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL13196555 | 0.85 | CRHBP (0.40) | ALDH1A1HPGDPDE7APKMSMN1; SMN2 | |
| SCHEMBL13196444 | 0.82 | CNR2 (0.40) | ALDH1A1HPGDPKMKDM4EPOLB | |
| SCHEMBL13196604 | 0.82 | CNR2 (0.40) | ALDH1A1PKMKDM4EPOLBLMNA | |
| SCHEMBL13196458 | 0.80 | NAMPT (0.40) | ALDH1A1PKMKDM4EPOLBLMNA | |
| SCHEMBL13196447 | 0.78 | CNR2 (0.37) | PKMKDM4EPOLBPKLRCNR2 | |
| SCHEMBL13196438 | 0.78 | CNR2 (0.37) | PKMKDM4EPOLBLMNAPKLR | |
| SCHEMBL13196449 | 0.75 | POLB (0.41) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL13196575 | 0.74 | CNR2 (0.40) | ALDH1A1HPGDKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL2779905 | 0.73 | CNR2 (0.65) | ALDH1A1KDM4EPOLBLMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |